Nausea and Vomiting. Cannabinoids are extremely effective
Cannabinoids are extremely effective in treating nausea, vomiting, and general sickness in many patients. It is particularly useful for cancer patients who choose to undergo chemotherapy and is recommended. THC is found to be superior to either Prochloperazine or Metoclopramide for pediatric cancer patients.
Cannabis may protect against osteoporosis
Studies indicate that cannabis use may protect against osteoporosis, otherwise known as brittle bone disease. In normal bone growth, there is a balance between osteoblasts (the bone-forming cells) and osteoclasts (the bone-reabsorbing cells). As we age, the osteoblasts slow down but osteoclasts continue to function normally and in some cases actually increase activity, which leads to the condition. Recently, the main components of the endocannabinoid system, namely the CB1 and CB2 receptors, along with the two main endocannabinoids, Anandamide and 2- AG, have been found in the human skeleton and they are reported to be involved in the regulation of bone metabolism.
Fat accumulation was prevented by cannabis use
CB1 receptor deficiency is believed to cause osteoporosis due to a marked increase in bone reabsorption, with an associated reduction in bone formation leading to increased fat cells in the bone marrow. During trials, this fat accumulation was prevented by cannabis use. Scientists now believe that the main physiologic involvement of specific CB2 receptors is to maintain a balance of bone remodeling, thus protecting the skeleton against age-related bone loss. Investigators at the Bone Laboratory of the Hebrew University in Jerusalem reported in the January 2006 issue of the Proceedings of the National Academy of Sciences that the administration of the synthetic cannabinoid agonist HU-308 slowed the development of osteoporosis, stimulated bone building, and reduced bone loss.